Table 1 Review of clinical, imaging, and genetic aspects of EE patients
From: Symptomatic eating epilepsy: two novel pediatric patients and review of literature
| authors, year [Ref] | n° of EE cases | mean age at eating sz onset (y) | sex (M/F) | trigger stimuli | imaging findings | genetic analysis |
|---|---|---|---|---|---|---|
| Singh et al., 2019 [29] | 12 | 13.5 y | 11 M; 1 F | eating alone (75%); eating + anxiety; eating + bathing; eating + spontaneously |
normal (7 pts); + 5 pts. (41.6%), focal/bilateral sclerosis or gliosis | na |
| von Stülpnagel et al., 2019 [2] | 8 | 6.9 y | 4 M; 4 F | biting; eating; chewing; oral sensory stimuli | normal | SYNGAP1 mutations |
|
Jagtap et al., 2016 [4] | 47 | 14.3 ± 9.8 y | 41 M; 6 F | eating; eating rice made food; oral sensory stimuli | + 16 pts. (34%), mainly PC lesions | na |
|
Yacubian et al., 2014 [30] | 3 | 15 y | 3 F | eating (independently of type of food) | normal | probably genetic due to familial clustering, but tested negative |
|
Sillanpää et al., 2014 [9] | 1 | 0 y | F | breast feeding | normal | na |
|
Patel et al., 2013 [31] | 6 | 11.3 ± 2.16 y | 3 M; 3 F | eating; eating rice made food; “thinking of eating” | + 5 pts. (83.3%), perysilvian F lobe and high F lesions | na |
|
Kokes et al., 2013 [32] | 6 | 20.3 y | 4 M; 2 F | chewing; swallowing; oral sensory stimuli | + 4 pts. (66.7%), L hemisphere lesions | na |
|
de Palma et al., 2012 [10] | 1 | 6 y | M |
eating; oral and gustatory sensory stimuli (mainly spicy food) | normal | MECP2 duplication |
| Roche Martínez et al., 2011 [11] | 1 | 16 y | F | eating (independently of type of food) | normal | Rett syndrome but MECP2, CDKL5, FOXG1 tested negative |
|
Bae et al., 2011 [12] | 2 | 39.5 y | 1 M; 1 F | eating (independently of type of food) | normal | na |
|
d’Orsi et al., 2007 [33] | 1 | 25 y | M |
chewing; eating; swallowing |
+ bilateral opercular dysplasia | na |
|
Loreto et al., 2000 [13] | 3 | 22.7 y | 2 M; 1 F | eating; sensory stimuli | + 2 pts. (66.7%), not specific | na |
|
Mandal et al., 1992 [34]a | 20 | na | 16 M; 4 F | eating; eating Indian, rice made food/ heavy meals | normal (in 7 pts. tested) | na |
|
Koul et al., 1991 [35]a | 78 | na | na | eating; swallowing | na | na |
|
Senanayake, 1990 [5] | 20 | 20 y | na | eating | na | probably genetic due to familial clustering |
|
Koul et al., 1989 [14] | 50 | 23.8 y | na | chewing; eating rice made food; swallowing | na | na |
|
Loiseau et al., 1986 [36] | 2 | 20.5 y | 2 M |
chewing (mainly); eating | na | na |
|
Nagaraja et al., 1984 [15] | 13 | 14 y | 8 M; 5 F | chewing; eating Indian, rice made food/heavy meals; drinking | na | na |
|
Aguglia et al., 1983 [3] | 3 | 21.3 y | 2 M; 1 F |
chewing; eating (independently of type of food) | na | na |
|
Ahuja et al., 1980 [16] | 3 | 21.7 y | 3 M | eating (only at home in 2 cases; both at home and outside in 1 case) | na | na |
|
Robertson et al., 1979 [37] | 1 | 14 y | M | eating (independently of type of food) | + internal capsule astrocytoma (involvement of the right caudate nucleus) | na |
|
Cirignotta et al., 1977 [38] | 1 | 16 y | F | eating (independently of type of food) | na | na |
|
Scollo-Lavizzari et al., 1967 [39] | 1 | 12 y | M |
chewing; eating; swallowing; sensory stimuli | na | na |