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Table 1 Ibuprofen and chickenpox

From: Serious infectious events and ibuprofen administration in pediatrics: a narrative review in the era of COVID-19 pandemic

Year 1st author (Ref) Children (N) Disorder Treatment Adverse events
1997 Choo [26] 7865 Chickenpox Ibuprofen SSTI
1999 Zerr [23] 48 Chickenpox Ibuprofen Necrotizing fascitis
2001 Lesko [27] 224 Chickenpox Ibuprofen +/− GAS infections and
     paracetamol soft tissues necrosis
2008 Mikaeloff [28] 140,111 Chickenpox Ibuprofen Cellulitis, abscess,
     (or other NSAIDs) fasciitis and necrosis
2008 Souyry [29] 266 Chickenpox Ibuprofen Serious necrotising
    and other (or other NSAIDs) soft-tissue infections
    viral infections   
2008 Dubos [30] 159 Chickenpox Ibuprofen Secondary bacterial
      skin complications
  1. GAS Group A streptococci, N Number of enrolled children, NSAIDs Non-steroidal anti-inflammatory drugs, Ref Reference number, SSTI Skin and soft tissue infection