| Author and year | Intervention | Control | Treatment duration | Follow up | Type of feeding |
|---|---|---|---|---|---|
| Savino F et al. 2010 [96] |
Lactobacillus reuteri DSM 17938 108 CFU (5 drops) |
Placebo (identical formulation but without live bacteria) | 21 days | No follow up | Exclusive breast-feeding |
| Szajewska H et al. 2013 [64] |
Lactobacillus reuteri DSM 17938 108 CFU (5 drops) |
Placebo (identical formulation but without live bacteria) | 21 days | 8 days | Exclusive or predominat (> 50%) breast-feeding |
| Chau K et al. 2015 [97] |
Lactobacillus reuteri DSM 17938 108 CFU (5 drops) |
Placebo (same excipient ingredients but without live bacteria) | 21 days | No follow up |
Exclusive breast-feeding |
| Sung V et al. 2014 [98] | Lactobacillus reuteri DSM 17938 108 CFU (5 drops) |
Placebo (maltodextrin in the same oil suspension) | 1 month | 5 months | Formula feeding, breast feeding |